N-Heterocyclic Carbene-Ruthenium Complexes: A Prominent Breakthrough in Metathesis Reactions

Sudheendran Mavila, N. Gabriel Lemcoff

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

The olefin metathesis reaction is considered to be an indispensable synthetic tool for both organic and polymer chemists. This chapter presents a brief survey of some interesting and useful modifications of N-heterocyclic carbene (NHC) ligands in ruthenium metathesis complexes, illustrated with their activity in various metathesis reactions using standard substrates. Among the NHCs used in the preparation of ruthenium complexes so far, the most successful and frequently studied complexes were those bearing imidazole or imidazolin-2-ylidene ligands. Initially, ruthenium complexes bearing unsymmetrically substituted NHCs were developed in order to improve the catalytic activity through increased basicity of the carbene. Unsymmetric diaryl substitution of the NHC backbone can promote new catalytic pathways leading to stereoselectivities not achievable by the standard symmetric substitution. Altering the NHC ring size may also bring about changes in the steric environment around the metal.

Original languageEnglish
Title of host publicationN-Heterocyclic Carbenes
Subtitle of host publicationEffective Tools for Organometallic Synthesis
PublisherWiley-Blackwell
Pages307-340
Number of pages34
Volume9783527334902
ISBN (Electronic)9783527671229
ISBN (Print)9783527334902
DOIs
StatePublished - 3 Nov 2014

Keywords

  • Imidazolin-2-ylidene ligands
  • Metathesis reaction
  • N-heterocyclic carbene (NHC)-ruthenium complexes

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