@article{aa8cc79840384312b23f5a5ffa10ff74,
title = "N-Heterocyclic carbene triazolium salts containing brominated aromatic motifs: Features and synthetic protocol",
abstract = "In this work, we provide a brief overview of the role of N-aryl substituents on triazolium N-heterocyclic carbene (NHC) catalysis. This synopsis provides context for the disclosed synthetic protocol for new chiral N-heterocyclic carbene (NHC) triazolium salts with brominated aromatic motifs. Incorporating brominated aryl rings into NHC structures is challenging, probably due to the substantial steric and electronic influence these substituents exert throughout the synthetic protocol. However, these exact characteristics make it an interesting N-aryl substituent, because the electronic and steric diversity it offers could find broad use in organometallic- A nd organo-catalysis. Following the synthetic reaction by NMR guided the extensive modification of a known protocol to enable the preparation of these challenging NHC pre-catalysts.",
keywords = "Arylhydrazine, De-silylation, NHC, Organocatalysis, Triazolium salts",
author = "Raed, {Anas Abo} and Vasudevan Dhayalan and Shahar Barkai and Anat Milo",
note = "Funding Information: Vasudevan Dhayalan obtained his MSc in Organic Chemistry (2005) and his PhD in Organic Chemistry (2011) at the University of Madras, India. He then joined the group of Prof. Masahiko Hayashi at Kobe University, Japan, as a postdoctoral researcher (2011– 2012). Later, he worked with Prof. Paul Knochel at the Ludwig-Maximilians-University Munich, Germany (2013–2015). In 2016, he joined the group of Prof. Anat Milo at the Ben-Gurion University of the Negev with a PBC outstanding postdoctoral research fellowship. Recently, he was awarded the prestigious Ramanujan fellowship from Science and Engineering Research Board (SERB) India. Funding Information: This research was supported by the Israel Science Foundation (Grant No. 1193/17). V.D. gratefully acknowledges the PBC for a postdoctoral fellowship and A.A.R. gratefully acknowledges the Kreitman school of Advanced Graduate Studies for the Chemo-tech PhD fellowship. Publisher Copyright: {\textcopyright} 2020 Swiss Chemical Society. All rights reserved.",
year = "2020",
month = nov,
day = "1",
doi = "10.2533/CHIMIA.2020.878",
language = "English",
volume = "74",
pages = "878--882",
journal = "Chimia",
issn = "0009-4293",
publisher = "Swiss Chemical Society",
number = "11",
}