Nanoengineered Antiviral Fibrous Arrays with Rose-Thorn-Inspired Architectures

Amir Nasajpour, Mohamadmahdi Samandari, Chandrashekhar D. Patil, Reza Abolhassani, Rahul K. Suryawanshi, Rainer Adelung, Horst Günter Rubahn, Ali Khademhosseini, Yogendra Kumar Mishra, Deepak Shukla, Ali Tamayol, Paul S. Weiss

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Herpes simplex virus (HSV) plagues billions of humans with infections globally. We have developed and demonstrated rose-thorn-inspired antiviral fibrous arrays by electrospinning a composite of polycaprolactone (PCL) polymer with a dispersion of anisotropic zinc oxide tetrapod nanoparticles (ZOTeN). This rose-thorn-mimicking material enables physical and chemical protection. Under blue-light stimulation, ZOTeN photocatalyzes the production of hydrogen peroxide for an accessible disinfection and sterilizing mechanism to prolong materials usage. Using scanning electron microscopy and X-ray photoelectron spectroscopy, we confirm the rose-thorn-inspired morphology and the chemical composition, respectively. The fibrous material has dose-dependent antiviral properties against both HSV-1 and HSV-2. The engineered mats can potentially be used for manufacturing antiviral garments, face coverings, and bandages.

Original languageEnglish
Pages (from-to)1566-1571
Number of pages6
JournalACS Materials Letters
Volume3
Issue number11
DOIs
StatePublished - 1 Nov 2021
Externally publishedYes

ASJC Scopus subject areas

  • General Chemical Engineering
  • Biomedical Engineering
  • General Materials Science

Fingerprint

Dive into the research topics of 'Nanoengineered Antiviral Fibrous Arrays with Rose-Thorn-Inspired Architectures'. Together they form a unique fingerprint.

Cite this