TY - JOUR
T1 - Nanoengineered Antiviral Fibrous Arrays with Rose-Thorn-Inspired Architectures
AU - Nasajpour, Amir
AU - Samandari, Mohamadmahdi
AU - Patil, Chandrashekhar D.
AU - Abolhassani, Reza
AU - Suryawanshi, Rahul K.
AU - Adelung, Rainer
AU - Rubahn, Horst Günter
AU - Khademhosseini, Ali
AU - Mishra, Yogendra Kumar
AU - Shukla, Deepak
AU - Tamayol, Ali
AU - Weiss, Paul S.
N1 - Publisher Copyright:
© 2021 American Chemical Society.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Herpes simplex virus (HSV) plagues billions of humans with infections globally. We have developed and demonstrated rose-thorn-inspired antiviral fibrous arrays by electrospinning a composite of polycaprolactone (PCL) polymer with a dispersion of anisotropic zinc oxide tetrapod nanoparticles (ZOTeN). This rose-thorn-mimicking material enables physical and chemical protection. Under blue-light stimulation, ZOTeN photocatalyzes the production of hydrogen peroxide for an accessible disinfection and sterilizing mechanism to prolong materials usage. Using scanning electron microscopy and X-ray photoelectron spectroscopy, we confirm the rose-thorn-inspired morphology and the chemical composition, respectively. The fibrous material has dose-dependent antiviral properties against both HSV-1 and HSV-2. The engineered mats can potentially be used for manufacturing antiviral garments, face coverings, and bandages.
AB - Herpes simplex virus (HSV) plagues billions of humans with infections globally. We have developed and demonstrated rose-thorn-inspired antiviral fibrous arrays by electrospinning a composite of polycaprolactone (PCL) polymer with a dispersion of anisotropic zinc oxide tetrapod nanoparticles (ZOTeN). This rose-thorn-mimicking material enables physical and chemical protection. Under blue-light stimulation, ZOTeN photocatalyzes the production of hydrogen peroxide for an accessible disinfection and sterilizing mechanism to prolong materials usage. Using scanning electron microscopy and X-ray photoelectron spectroscopy, we confirm the rose-thorn-inspired morphology and the chemical composition, respectively. The fibrous material has dose-dependent antiviral properties against both HSV-1 and HSV-2. The engineered mats can potentially be used for manufacturing antiviral garments, face coverings, and bandages.
UR - https://www.scopus.com/pages/publications/85117761943
U2 - 10.1021/acsmaterialslett.1c00419
DO - 10.1021/acsmaterialslett.1c00419
M3 - Article
AN - SCOPUS:85117761943
SN - 2639-4979
VL - 3
SP - 1566
EP - 1571
JO - ACS Materials Letters
JF - ACS Materials Letters
IS - 11
ER -
