Abstract
Cardiac tissue engineering (CTE) aims to create contractile tissues to replace damaged or missing myocardial tissues. Biomaterials/scaffolds constitute a major component in various strategies of CTE, as stand-alone treatments or in combination with cells and/or bioactive molecules. This chapter describes the recent applications of nanomaterials and nanofabrication methods in CTE scaffolds to mimic the structural and architectural properties of the cardiac extracellular matrix (ECM) and to enable controllable and efficient single cell stimulation. Emphasis will be given to the implementation of magnetic field stimulation in CTE, attained by impregnating nano-magnetites into the CTE scaffold. Nanotechnology has already led to engineered cardiac tissues better suited for implantation.
Original language | English |
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Title of host publication | Nanomaterials in Tissue Engineering |
Subtitle of host publication | Fabrication and Applications |
Publisher | Elsevier Ltd. |
Pages | 244-275 |
Number of pages | 32 |
ISBN (Print) | 9780857095961 |
DOIs | |
State | Published - 1 Jan 2013 |
Keywords
- Alginate scaffolds
- Magneto-mechanical cell stimulation
- Nanofabrication
- Nanoparticles
- Nanostructures
- Nanotechnology
- Tissue engineering
ASJC Scopus subject areas
- General Materials Science