Nanomaterials for cardiac tissue engineering

Y. Sapir, B. Polyak, S. Cohen

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Cardiac tissue engineering (CTE) aims to create contractile tissues to replace damaged or missing myocardial tissues. Biomaterials/scaffolds constitute a major component in various strategies of CTE, as stand-alone treatments or in combination with cells and/or bioactive molecules. This chapter describes the recent applications of nanomaterials and nanofabrication methods in CTE scaffolds to mimic the structural and architectural properties of the cardiac extracellular matrix (ECM) and to enable controllable and efficient single cell stimulation. Emphasis will be given to the implementation of magnetic field stimulation in CTE, attained by impregnating nano-magnetites into the CTE scaffold. Nanotechnology has already led to engineered cardiac tissues better suited for implantation.

Original languageEnglish
Title of host publicationNanomaterials in Tissue Engineering
Subtitle of host publicationFabrication and Applications
PublisherElsevier Ltd.
Pages244-275
Number of pages32
ISBN (Print)9780857095961
DOIs
StatePublished - 1 Jan 2013

Keywords

  • Alginate scaffolds
  • Magneto-mechanical cell stimulation
  • Nanofabrication
  • Nanoparticles
  • Nanostructures
  • Nanotechnology
  • Tissue engineering

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