Nanoparticle-Assisted STED, theory, and Experimental Demonstration

Yannick Sonnefraud; Yonatan Sivan; Hugo G Sinclair; Christopher W Dunsby; Mark A Neil; Paul M French; Stefan A Maier

Nanoparticle-Assisted STED, theory, and Experimental Demonstration

Yannick Sonnefraud, Yonatan Sivan, Hugo G Sinclair, Christopher W Dunsby, Mark A Neil, Paul M French, Stefan A Maier

Unit of Photonics and Electro-Optics Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

Original language	English GB
Title of host publication	Proceedings of SPIE: Nanoimaging and Nanospectroscopy II
Editors	Prabhat Verma, Alexander Egner
Publisher	SPIE
Number of pages	1
Volume	9169
State	Published - 2014

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http://doi.org/10.1117/12.2060993

Cite this

@inproceedings{91dceeadeebc4d43b10b44b4aceb8ed0,

title = "Nanoparticle-Assisted STED, theory, and Experimental Demonstration",

abstract = "We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.",

author = "Yannick Sonnefraud and Yonatan Sivan and Sinclair, {Hugo G} and Dunsby, {Christopher W} and Neil, {Mark A} and French, {Paul M} and Maier, {Stefan A}",

year = "2014",

language = "אנגלית",

volume = "9169",

editor = "Prabhat Verma and Egner, {Alexander }",

booktitle = "Proceedings of SPIE: Nanoimaging and Nanospectroscopy II",

publisher = "SPIE",

address = "ארצות הברית",

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TY - GEN

T1 - Nanoparticle-Assisted STED, theory, and Experimental Demonstration

AU - Sonnefraud, Yannick

AU - Sivan, Yonatan

AU - Sinclair, Hugo G

AU - Dunsby, Christopher W

AU - Neil, Mark A

AU - French, Paul M

AU - Maier, Stefan A

PY - 2014

Y1 - 2014

N2 - We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

AB - We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

M3 - פרסום בספר כנס

VL - 9169

BT - Proceedings of SPIE: Nanoimaging and Nanospectroscopy II

A2 - Verma, Prabhat

A2 - Egner, Alexander

PB - SPIE

ER -

Nanoparticle-Assisted STED, theory, and Experimental Demonstration

Abstract

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