Nanoparticle-Assisted STED, theory, and Experimental Demonstration: (presentation video)

Yannick Sonnefraud; Yonatan Sivan; Hugo G Sinclair; Christopher W Dunsby; Mark A Neil; Paul M French; Stefan A Maier

doi:10.1117/12.2060993

Nanoparticle-Assisted STED, theory, and Experimental Demonstration: (presentation video)

Yannick Sonnefraud
, Yonatan Sivan
, Hugo G Sinclair
, Christopher W Dunsby
, Mark A Neil
, Paul M French
, Stefan A Maier

Research output: Contribution to conference › Paper

Abstract

We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

Original language	English
Number of pages	1
DOIs	https://doi.org/10.1117/12.2060993
State	Published - Nov 2014

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title = "Nanoparticle-Assisted STED, theory, and Experimental Demonstration: (presentation video)",

abstract = "We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores. ",

author = "Yannick Sonnefraud and Yonatan Sivan and Sinclair, \{Hugo G\} and Dunsby, \{Christopher W\} and Neil, \{Mark A\} and French, \{Paul M\} and Maier, \{Stefan A\}",

year = "2014",

month = nov,

doi = "10.1117/12.2060993",

language = "English",

}

TY - CONF

T1 - Nanoparticle-Assisted STED, theory, and Experimental Demonstration

T2 - (presentation video)

AU - Sonnefraud, Yannick

AU - Sivan, Yonatan

AU - Sinclair, Hugo G

AU - Dunsby, Christopher W

AU - Neil, Mark A

AU - French, Paul M

AU - Maier, Stefan A

PY - 2014/11

Y1 - 2014/11

N2 - We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

AB - We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Moreover, we present experimental evidence that an optimum resolution, limited by the sizes of the particles used, can be reached for the hybrid NPs for a power of the STED beam one order of magnitude smaller than for the bare cores.

U2 - 10.1117/12.2060993

DO - 10.1117/12.2060993

M3 - Paper

ER -

Nanoparticle-Assisted STED, theory, and Experimental Demonstration: (presentation video)

Abstract

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