Nanoparticle-Assisted Stimulated-Emission-Depletion Nanoscopy

Yonatan Sivan, Yannick Sonnefraud, Stéphane Kéna-Cohen, John B. Pendry, Stefan A. Maier

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Figure Persented: We show that metal nanoparticles can be used to improve the performance of super-resolution fluorescence nanoscopes based on stimulated-emission-depletion (STED). Compared with a standard STED nanoscope, we show theoretically a resolution improvement by more than an order of magnitude, or equivalently, depletion intensity reductions by more than 2 orders of magnitude and an even stronger photostabilization. Our scheme may allow improvement of existing STED nanoscopes and assist in the development of low-power, low-cost nanoscopes. This has the potential to increase the availability of STED nanoscopes and lead to a significant expansion of our understanding of biological and biochemical phenomena occurring on the nanoscale.

Original languageEnglish
Pages (from-to)5291-5296
Number of pages6
JournalACS Nano
Issue number6
StatePublished - 26 Jun 2012
Externally publishedYes


  • STED microscopy
  • nanoshells
  • photobleaching
  • plasmonics
  • super-resolution
  • triplets

ASJC Scopus subject areas

  • Materials Science (all)
  • Engineering (all)
  • Physics and Astronomy (all)


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