Nasal ketamine for paediatric premedication

Natan Weksler, Leon Ovadia, Gabi Muati, Anatoli Stav

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


Ketamine in a dose of 6 mg · kg-1 was nasally administered in 86 healthy children (ASA I and II), aged from two to five years undergoing elective general, urological or plastic surgery, 20 to 40 min before the scheduled surgery time. These children were compared with 62 others, also aged from two to five years, in whom promethazine and meperidine, 1 mg · kg-1 of each, were injected im. Sedation was started as excellent in 48 and as adequate in 19 children in the ketamine group, compared with nine and 12 respectively in Group 2 (P < 0.05), while salivation was similar in both groups. We conclude that nasal ketamine is an alternative to im preanaesthetic sedation administration in children aged from two to five years.

Original languageEnglish
Pages (from-to)119-121
Number of pages3
JournalCanadian Journal of Anaesthesia
Issue number2
StatePublished - 1 Feb 1993
Externally publishedYes


  • anaesthesia: paediatric
  • anaesthetics, intravenous: ketamine
  • premedication: ketamine


Dive into the research topics of 'Nasal ketamine for paediatric premedication'. Together they form a unique fingerprint.

Cite this