Near fatal acute colchicine intoxication in a child. A case report

Aviv Goldbart, Joseph Press, Shaul Sofer, Joseph Kapelushnik

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


An 8-year-old child with familial Mediterranean fever exhibited signs of colchicine intoxication while receiving prophylactic doses of the drug. She developed gastrointestinal, central nervous system, cardiovascular and haematological disturbances. Over 2 months she had been drinking high doses of natural grapefruit juice which, combined with long-term colchicine therapy and a viral upper respiratory tract infection, increased her susceptibility to the drug. Conclusion: To the best of our knowledge, this is the first time colchicine intoxication in this age group has been described in the English literature.

Original languageEnglish
Pages (from-to)895-897
Number of pages3
JournalEuropean Journal of Pediatrics
Issue number12
StatePublished - 1 Jan 2000
Externally publishedYes


  • Colchicine intoxication
  • Familial Mediterranean fever
  • Grapefruit juice

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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