Neonatal candidiasis: Epidemiologic, clinical and therapeutic aspects

Eugene Leibovitz

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations


    Candida infections are frequent and major causes of septicemia in neonatal ICUs, and they are associated with high morbidity and mortality rates. Low-birth-weight preterm infants are especially vulnerable to these devastating infections. The most frequently encountered fungal infections are caused by Candida albicans or Candida parapsilosis. Candidal infections in very low-birth-weight neonates may present as 3 distinct syndromes: congenital candidiasis, catheter-associated fungemia, and disseminated candidiasis. Amphotericin B (with or without flucytosine) is the treatment of choice for Candida infections in neonates, but its use is often limited by severe side effects. Possible alternatives to amphotericin B include triazoles (such as fluconazole) and lipid preparations of amphotericin B.

    Original languageEnglish
    Pages (from-to)494-498
    Number of pages5
    JournalInfections in Medicine
    Issue number10
    StatePublished - 1 Oct 2003


    • Amphotericin B
    • Candida
    • Neonatal ICU
    • Very low-birth-weight infants

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Infectious Diseases


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