Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy

Hanna Shalev; Melly Ohali; Oren Abramson; Moshe Phillip

doi:10.1016/S0022-3476(94)70204-7

Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy

Hanna Shalev, Melly Ohali, Oren Abramson, Moshe Phillip

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E₂ levels decreased fourfold to eightfold. (J PEDIATR 1994;125:246-8).

Original language	English
Pages (from-to)	246-248
Number of pages	3
Journal	Journal of Pediatrics
Volume	125
Issue number	2
DOIs	https://doi.org/10.1016/S0022-3476(94)70204-7
State	Published - 1 Jan 1994

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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title = "Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy",

abstract = "We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E2 levels decreased fourfold to eightfold. (J PEDIATR 1994;125:246-8).",

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AB - We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E2 levels decreased fourfold to eightfold. (J PEDIATR 1994;125:246-8).

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Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy

Abstract

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