Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy

Hanna Shalev, Melly Ohali, Oren Abramson, Moshe Phillip

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations


    We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E2 levels decreased fourfold to eightfold. (J PEDIATR 1994;125:246-8).

    Original languageEnglish
    Pages (from-to)246-248
    Number of pages3
    JournalJournal of Pediatrics
    Issue number2
    StatePublished - 1 Jan 1994

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health


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