Abstract
We describe the occurrence of a nephrotic syndrome in association with transitional cell carcinoma of the bladder. The proteinuria disappeared several weeks after removal of the tumor. Light and electron microscopy were compatible with a minimal-change lesion, but immunofluorescence showed linear immunoglobulin deposition. Immunoglobulins eluted from the tumor reacted specifically with the kidney and vice versa. We conclude that antibody formation against a specific component of basement membrane common to both kidney and tumor gave rise to the nephropathy in this case.
Original language | English |
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Pages (from-to) | 36-39 |
Number of pages | 4 |
Journal | Nephron |
Volume | 52 |
Issue number | 1 |
DOIs | |
State | Published - 1 Jan 1989 |
ASJC Scopus subject areas
- Physiology
- Nephrology
- Physiology (medical)
- Urology