Neurobiology of cancer: Interactions between nervous, endocrine and immune systems as a base for monitoring and modulating the tumorigenesis by the brain

Boris Mravec, Yori Gidron, Ivan Hulin

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

The interactions between the nervous, endocrine and immune systems are studied intensively. The communication between immune and cancer cells, and multilevel and bi-directional interactions between the nervous and immune systems constitute the basis for a hypothesis assuming that the brain might monitor and modulate the processes associated with the genesis and progression of cancer. The aim of this article is to describe the data supporting this hypothesis.

Original languageEnglish
Pages (from-to)150-163
Number of pages14
JournalSeminars in Cancer Biology
Volume18
Issue number3
DOIs
StatePublished - 1 Jun 2008
Externally publishedYes

Keywords

  • Cholinergic anti-inflammatory pathway
  • Innervation of the tumors
  • Neurobiology of cancer
  • Neurotransmitters
  • Vagus nerve

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