Neurochemical mechanisms of action of ECS: Evidence from in vivo studies

Michael E. Newman; Eitan Gur; Baruch Shapira; Bernard Lerer

Neurochemical mechanisms of action of ECS: Evidence from in vivo studies

Michael E. Newman, Eitan Gur, Baruch Shapira, Bernard Lerer

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Recent advances in receptor pharmacology and in the understanding of intracellular signal-transduction systems have given rise to new theories of the mechanism of action of antidepressant drugs. The relevance of these theories to the antidepressant mechanism(s) of electroconvulsive shock (ECS) is discussed, with a view to increasing understanding of the mechanism of electroconvulsive therapy (ECT). Particular attention is given to results obtained with in vivo methods both in experimental animals and in human subjects.

Original language	English
Pages (from-to)	153-171
Number of pages	19
Journal	Journal of ECT
Volume	14
Issue number	3
State	Published - 3 Oct 1998
Externally published	Yes

Keywords

Antidepressant
Cyclic AMP
Electroconvulsive shock
Noradrenaline
Serotonin

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Psychiatry and Mental health

Cite this

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abstract = "Recent advances in receptor pharmacology and in the understanding of intracellular signal-transduction systems have given rise to new theories of the mechanism of action of antidepressant drugs. The relevance of these theories to the antidepressant mechanism(s) of electroconvulsive shock (ECS) is discussed, with a view to increasing understanding of the mechanism of electroconvulsive therapy (ECT). Particular attention is given to results obtained with in vivo methods both in experimental animals and in human subjects.",

keywords = "Antidepressant, Cyclic AMP, Electroconvulsive shock, Noradrenaline, Serotonin",

author = "Newman, {Michael E.} and Eitan Gur and Baruch Shapira and Bernard Lerer",

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T2 - Evidence from in vivo studies

AU - Newman, Michael E.

AU - Gur, Eitan

AU - Shapira, Baruch

AU - Lerer, Bernard

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Y1 - 1998/10/3

N2 - Recent advances in receptor pharmacology and in the understanding of intracellular signal-transduction systems have given rise to new theories of the mechanism of action of antidepressant drugs. The relevance of these theories to the antidepressant mechanism(s) of electroconvulsive shock (ECS) is discussed, with a view to increasing understanding of the mechanism of electroconvulsive therapy (ECT). Particular attention is given to results obtained with in vivo methods both in experimental animals and in human subjects.

AB - Recent advances in receptor pharmacology and in the understanding of intracellular signal-transduction systems have given rise to new theories of the mechanism of action of antidepressant drugs. The relevance of these theories to the antidepressant mechanism(s) of electroconvulsive shock (ECS) is discussed, with a view to increasing understanding of the mechanism of electroconvulsive therapy (ECT). Particular attention is given to results obtained with in vivo methods both in experimental animals and in human subjects.

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KW - Cyclic AMP

KW - Electroconvulsive shock

KW - Noradrenaline

KW - Serotonin

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IS - 3

ER -

Neurochemical mechanisms of action of ECS: Evidence from in vivo studies

Abstract

Keywords

ASJC Scopus subject areas

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