New aspects in placental drug transfer

Gershon Holcberg, Marina Tsadkin-Tamir, Olga Sapir, Mahmoud Huleihel, Moshe Mazor, Zvi Ben Zvi

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


The human placenta Is the interface between the mother and fete in the uterus. Until recently it was generally believed that the uterus provides a protective environment for the fetus. It is now accepted that any chemical substance, including any therapeutic agent, administered to a mother is able to permeate across the placental barrier. Unfortunately, the placental transfer of substances and their distribution in the placenta Is not weft established. Understanding the structure of placental transporters and their function rnay serve as the ideal tool for drug development and the cure of mother and fetus during pregnancy.

Original languageEnglish
Pages (from-to)873-876
Number of pages4
JournalIsrael Medical Association Journal
Issue number12
StatePublished - 1 Dec 2003


  • Hypoglycemic drugs
  • P-glycoprotein
  • Placenta
  • Transporters

ASJC Scopus subject areas

  • Medicine (all)


Dive into the research topics of 'New aspects in placental drug transfer'. Together they form a unique fingerprint.

Cite this