New insights into the structural organization of eukaryotic and prokaryotic cytoskeletons using cryo-electron tomography

Julia Kürner; Ohad Medalia; Alexandros A. Linaroudis; Wolfgang Baumeister

doi:10.1016/j.yexcr.2004.08.005

New insights into the structural organization of eukaryotic and prokaryotic cytoskeletons using cryo-electron tomography

Julia Kürner
, Ohad Medalia
, Alexandros A. Linaroudis
, Wolfgang Baumeister

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Cryo-electron tomography (cryo-ET) is an emerging imaging technology that combines the potential of three-dimensional (3-D) imaging at molecular resolution (<5 nm) with a close-to-life preservation of the specimen. In conjunction with pattern recognition techniques, it enables us to map the molecular landscape inside cells. The application of cryo-ET to intact cells provides novel insights into the structure and the spatial organization of the cytoskeleton in prokaryotic and eukaryotic cells.

Original language	English
Pages (from-to)	38-42
Number of pages	5
Journal	Experimental Cell Research
Volume	301
Issue number	1
DOIs	https://doi.org/10.1016/j.yexcr.2004.08.005
State	Published - 15 Nov 2004
Externally published	Yes

Keywords

Actin
Electron microscopy
Macromolecular structure
Motility
Spiroplasma

ASJC Scopus subject areas

Cell Biology

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10.1016/j.yexcr.2004.08.005

Cite this

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title = "New insights into the structural organization of eukaryotic and prokaryotic cytoskeletons using cryo-electron tomography",

abstract = "Cryo-electron tomography (cryo-ET) is an emerging imaging technology that combines the potential of three-dimensional (3-D) imaging at molecular resolution (<5 nm) with a close-to-life preservation of the specimen. In conjunction with pattern recognition techniques, it enables us to map the molecular landscape inside cells. The application of cryo-ET to intact cells provides novel insights into the structure and the spatial organization of the cytoskeleton in prokaryotic and eukaryotic cells.",

keywords = "Actin, Electron microscopy, Macromolecular structure, Motility, Spiroplasma",

author = "Julia K{\"u}rner and Ohad Medalia and Linaroudis, \{Alexandros A.\} and Wolfgang Baumeister",

year = "2004",

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doi = "10.1016/j.yexcr.2004.08.005",

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volume = "301",

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journal = "Experimental Cell Research",

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T1 - New insights into the structural organization of eukaryotic and prokaryotic cytoskeletons using cryo-electron tomography

AU - Kürner, Julia

AU - Medalia, Ohad

AU - Linaroudis, Alexandros A.

AU - Baumeister, Wolfgang

PY - 2004/11/15

Y1 - 2004/11/15

N2 - Cryo-electron tomography (cryo-ET) is an emerging imaging technology that combines the potential of three-dimensional (3-D) imaging at molecular resolution (<5 nm) with a close-to-life preservation of the specimen. In conjunction with pattern recognition techniques, it enables us to map the molecular landscape inside cells. The application of cryo-ET to intact cells provides novel insights into the structure and the spatial organization of the cytoskeleton in prokaryotic and eukaryotic cells.

AB - Cryo-electron tomography (cryo-ET) is an emerging imaging technology that combines the potential of three-dimensional (3-D) imaging at molecular resolution (<5 nm) with a close-to-life preservation of the specimen. In conjunction with pattern recognition techniques, it enables us to map the molecular landscape inside cells. The application of cryo-ET to intact cells provides novel insights into the structure and the spatial organization of the cytoskeleton in prokaryotic and eukaryotic cells.

KW - Actin

KW - Electron microscopy

KW - Macromolecular structure

KW - Motility

KW - Spiroplasma

UR - https://www.scopus.com/pages/publications/6344260555

U2 - 10.1016/j.yexcr.2004.08.005

DO - 10.1016/j.yexcr.2004.08.005

M3 - Review article

AN - SCOPUS:6344260555

SN - 0014-4827

VL - 301

SP - 38

EP - 42

JO - Experimental Cell Research

JF - Experimental Cell Research

IS - 1

ER -

New insights into the structural organization of eukaryotic and prokaryotic cytoskeletons using cryo-electron tomography

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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