Abstract
We report a new MCR involving the reaction of isatoic anhydrides, allyl amine and o-bromo arylaldehydes in the presence of Pd(OAc)2, X-Phos and air to afford various isoquinolino[1,2-b]quinazolinones as new cytotoxic agents. The strategy was extended successfully towards the synthesis of a methyl analogue of 7,8-dehydrorutaecarpine.
Original language | English |
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Pages (from-to) | 49324-49328 |
Number of pages | 5 |
Journal | RSC Advances |
Volume | 4 |
Issue number | 90 |
DOIs | |
State | Published - 1 Jan 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- General Chemistry
- General Chemical Engineering