TY - JOUR
T1 - Newborn Auditory Brainstem Responses in Children with Developmental Disabilities
AU - Delgado, Christine F.
AU - Simpson, Elizabeth A.
AU - Zeng, Guangyu
AU - Delgado, Rafael E.
AU - Miron, Oren
N1 - Funding Information:
Rafael E. Delgado is the Director of Research and Software Development for Intelligent Hearing Systems Corporation (IHS). Auditory brainstem response (ABR) data were acquired using IHS equipment. Rafael Delgado was not involved in the data collection/newborn screening process. The remaining authors have no financial relationships relevant to this article to disclose. The funding was provided by National Science Foundation (Grant No. NSF CAREER Award 1653737) and National Institutes of Health (Grant No. NIH SBIR 1R43DC018430-01).
Funding Information:
The support of the Florida Department of Education and MEDNAX for providing the records is gratefully acknowledged. The authors would also like to recognize and thank Olga Camacho, Antonio Gonzalez, and Jillian Gerstenberger for their assistance in preparing the datasets and Chris Gralapp, CMI for the artwork used in Fig. 1.
Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - We integrated data from a newborn hearing screening database and a preschool disability database to examine the relationship between newborn click evoked auditory brainstem responses (ABRs) and developmental disabilities. This sample included children with developmental delay (n = 2992), speech impairment (SI, n = 905), language impairment (n = 566), autism spectrum disorder (ASD, n = 370), and comparison children (n = 128,181). We compared the phase of the ABR waveform, a measure of sound processing latency, across groups. Children with SI and children with ASD had greater newborn ABR phase values than both the comparison group and the developmental delay group. Newborns later diagnosed with SI or ASD have slower neurological responses to auditory stimuli, suggesting sensory differences at birth.
AB - We integrated data from a newborn hearing screening database and a preschool disability database to examine the relationship between newborn click evoked auditory brainstem responses (ABRs) and developmental disabilities. This sample included children with developmental delay (n = 2992), speech impairment (SI, n = 905), language impairment (n = 566), autism spectrum disorder (ASD, n = 370), and comparison children (n = 128,181). We compared the phase of the ABR waveform, a measure of sound processing latency, across groups. Children with SI and children with ASD had greater newborn ABR phase values than both the comparison group and the developmental delay group. Newborns later diagnosed with SI or ASD have slower neurological responses to auditory stimuli, suggesting sensory differences at birth.
KW - Auditory brainstem response
KW - Autism spectrum disorder
KW - Developmental disabilities
KW - Early identification
KW - Speech impairment
UR - http://www.scopus.com/inward/record.url?scp=85148555253&partnerID=8YFLogxK
U2 - 10.1007/s10803-021-05126-1
DO - 10.1007/s10803-021-05126-1
M3 - Article
C2 - 34181140
AN - SCOPUS:85148555253
SN - 0162-3257
VL - 53
SP - 776
EP - 788
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 2
ER -