Newly Emerged 2D Mesoporous Silica Nanoparticles: Role in Target-Setting Biomedicines

Two-dimensional (2D) material is currently a major focus in materials science research with significant efforts made on synthesis, property characterization, and technological application. These materials come in wide varieties of chemical compositions and forms which enable its suitability for application in the areas of electronics, sensors, coatings, barriers, energy storage and conversion, and biomedicine. Application of synthetic 2D nanosheets for biomedical applications including human health has been envisaged by studying the biological and environmental interactions. 2D materials exhibit wide range of behaviors, reflecting the diversity in their chemical compositions, and undergo reactive dissolution processes which are critical for understanding their behaviors and interpreting the biological response data. This review attempts to cover up-to-date account on the contemporary literature in biological responses with reference to 2D materials. This also focuses on the mesoporous silica nanoparticles in order to provide insight into its essential chemical behavior and application. The review attempts to construct a framework for detailed investigation on biological evaluation of nanomaterials. It describes a series of methodology for high-priority research in the areas like the interface of cancer chemotherapy which could generate opportunities for safe and successful development of technologies related to 2D nanomaterials.