Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition

Keyphrases

• Aggregate Formation 20%
• Antihelmintics 20%
• Autophagy 60%
• Cell Population 20%
• Damaged Proteins 20%
• Disease-related Proteins 40%
• Ectopic Expression 20%
• Large Aggregates 40%
• Long-lived 20%
• Low Solubility 20%
• Lys63 20%
• Lysosome 60%
• Lysosome Distribution 20%
• Misfolded Proteins 20%
• MTOR Inhibitor 20%
• Neuroblastoma Cells 20%
• Neurodegenerative Diseases 20%
• Niclosamide 100%
• Poorly Soluble 20%
• Proteasome Activity 40%
• Proteasome Inhibition 100%
• Protein Aggregation 20%
• Rapamycin 20%
• Short-lived Protein 20%
• Soluble Protein 20%
• Stably Expressing 20%
• Tissue Culture Cells 20%
• Ubiquitin 100%
• Ubiquitin Conjugates 20%
• Ubiquitin Fusion Protein 20%
• Ubiquitin-proteasome System 20%
• Ubiquitinated Proteins 60%

Biochemistry, Genetics and Molecular Biology

• Autophagy 30%
• Conjugate 10%
• Ectopic Expression 10%
• Fusion Protein 10%
• Lysine 10%
• Lysosome 40%
• Proteasome 100%
• Protein Aggregation 10%
• Soluble Protein 10%
• Tissue Culture Cell 10%
• Ubiquitin 100%

Immunology and Microbiology

• Anthelmintic 10%
• Autophagy 30%
• Cell Population 10%
• Conjugate 10%
• Ectopic Expression 10%
• Lysosome 40%
• Neuroblastoma Cell 10%
• Proteasome 100%
• Protein Aggregation 10%
• Sirolimus 10%
• Tissue Culture Cell 10%