Nifedipine in the Treatment of Hypertension in the Elderly

Jochanan Stessman; Bonnie Leibel; Yoram Yagil; Rami Eliakim; Ori Ben‐Ishay

doi:10.1002/j.1552-4604.1985.tb02824.x

Nifedipine in the Treatment of Hypertension in the Elderly

Jochanan Stessman, Bonnie Leibel, Yoram Yagil, Rami Eliakim, Ori Ben‐Ishay

Research output: Contribution to journal › Article › peer-review

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Abstract

The effect of nifedipine monotherapy, retard tablets, 20 mg bid, was evaluated in 23 hypertensive patients, mean age, 79 ± 2 years. Twenty‐one patients completed an eight‐week study. Blood pressure (BP) decreased to 160/90 mm Hg in 15 patients; in four additional patients diastolic BP dropped by 15% to 28%. In a subset of five patients with isolated systolic hypertension, a significant reduction in systolic BP was noted. Side effects were relatively mild and only two patients discontinued the study. The results suggest that nifedipine monotherapy offers an alternative, logic, therapeutic approach to hypertension in the elderly. 1985 American College of Clinical Pharmacology

Original language	English
Pages (from-to)	193-196
Number of pages	4
Journal	Journal of Clinical Pharmacology
Volume	25
Issue number	3
DOIs	https://doi.org/10.1002/j.1552-4604.1985.tb02824.x
State	Published - 1 Jan 1985
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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10.1002/j.1552-4604.1985.tb02824.x

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AU - Ben‐Ishay, Ori

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AB - The effect of nifedipine monotherapy, retard tablets, 20 mg bid, was evaluated in 23 hypertensive patients, mean age, 79 ± 2 years. Twenty‐one patients completed an eight‐week study. Blood pressure (BP) decreased to 160/90 mm Hg in 15 patients; in four additional patients diastolic BP dropped by 15% to 28%. In a subset of five patients with isolated systolic hypertension, a significant reduction in systolic BP was noted. Side effects were relatively mild and only two patients discontinued the study. The results suggest that nifedipine monotherapy offers an alternative, logic, therapeutic approach to hypertension in the elderly. 1985 American College of Clinical Pharmacology

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Nifedipine in the Treatment of Hypertension in the Elderly

Abstract

ASJC Scopus subject areas

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