Nitrite is a very effective inducer of nitrate reductase. Nitrate induces the enzyme in darkness only upon addition of suitable sources of reducing equivalent which permit the formation of nitrite; nitrite itself brings about induction of the enzyme in darkness without supplementation of exogenous reducing cofactors. Inhibition of constitutive nitrate reductase by tungstate prevents induction of the enzyme by nitrate but not by nitrite. Since nitrate induces the enzyme only under conditions allowing production of nitrite while the induction capacity of nitrite is free of this constraint, nitrate reductase be considered a product‐inducible rather than a substrate‐inducible enzyme.
|Number of pages||6|
|Journal||European Journal of Biochemistry|
|State||Published - 1 Jan 1974|
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