Abstract
The invention relates to a targeting complex, capable of targeting an active substance to a target cell, said complex comprising: a target recognition segment comprising one of NKp46, NKp30, NKp44 or a functional fragment thereof; and an active segment comprising an active substance such as cytotoxic moiety; an imaging moiety; or an Ig fragment. The targeting complex of the invention serves as a therapeutic agents for the treatment of pathologies associated with viral infections or cancer and for the imaging and monitoring of cancer.
| Original language | English |
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| Patent number | WO0208287 |
| IPC | A61K 38/ 00 A N |
| Priority date | 20/07/00 |
| State | Published - 31 Jan 2002 |