N,N‐Dichlorourethane—A Selective Chlorination Reagent; Synthesis of Corticoids

Yehuda Mazur, Zvi Cohen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction of a double bond between C‐9 and C‐11 of the steroid skeleton can be accomplished by (i) chlorination of the saturated steroid with N, N‐dichlorourethane (EtOCONCl2) followed by (ii) dehydrochlorination with AgClO4. The products, e.g.(1), can easily be functionalized at C‐11. (Figure Presented.)

Original languageEnglish
Pages (from-to)281-282
Number of pages2
JournalAngewandte Chemie - International Edition
Issue number4
StatePublished - 1 Jan 1978
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry (all)


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