Non-cytotoxic modified cells and use thereof

Alon Monsonego (Inventor), Angel Porgador (Inventor), Roee Atlas (Inventor)

Research output: Patent


Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.

Original languageEnglish
Patent numberAU2017342176
IPCC12N 5/ 10 A I
Priority date10/10/17
StatePublished - 2 May 2019


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