Abstract
Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.
| Original language | English |
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| Patent number | CA3039774 |
| IPC | C12N 5/ 10 A I |
| Priority date | 10/10/17 |
| State | Published - 19 Apr 2018 |