Abstract
The bipolar affective disorder is long been speculated to have an autonomic involvement. Nonlinear analysis of heart rate variability has recently been shown to be a reliable noninvasive test for quantitative assessment of the central sympathovagal interaction that modulates cardiovascular autonomic function. We studied 32 euthymic bipolar patients and 24 controls. A high-resolution electrocardiogram was obtained during complete rest. Nonlinear analysis (Poincare plot, largest Lyaponuv exponent, minimal embedding dimension, symbolic dynamic) was used. There wasn't a statistically significant difference in the nonlinear analysis of the heart rate variability, between the euthymic bipolar patients and controls, in the rest situation. The nonlinear analysis of heart rate variability didn't support the notation that there is a disturbance in the autonomic nerves system of bipolar patients in the euthymic state.
Original language | English |
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Pages (from-to) | 127-131 |
Number of pages | 5 |
Journal | Autonomic Neuroscience: Basic and Clinical |
Volume | 117 |
Issue number | 2 |
DOIs | |
State | Published - 7 Feb 2005 |
Externally published | Yes |
Keywords
- Autonomic nervous system
- Bipolar disorder
- Chaos theory
- Heart rate variability
- Nonlinear analysis
ASJC Scopus subject areas
- Endocrine and Autonomic Systems
- Clinical Neurology
- Cellular and Molecular Neuroscience