Nonpharmacologic treatment of resistant hypertensives by device-guided slow breathing exercises

Reuven Viskoper, Irena Shapira, Rita Priluck, Rina Mindlin, Larissa Chornia, Anny Laszt, Dror Dicker, Benjamin Gavish, Ariela Alter

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Background: Recent studies have demonstrated the antihypertensive effect of slow breathing exercises, guided interactively by a device, in patients with uncontrolled blood pressure (BP) without changing medication. This study examined the response to the same treatment protocol in resistant hypertensives. Methods: Seventeen resistant hypertensives exercised device-guided slow breathing for 8 weeks, 15 min daily, and self-monitored BP. Data stored in the devices were collected on a PC-based system. Clinical outcomes were office and home BP changes from baseline to end values. Results: Significant reductions in both office BP (-12.9/-6.9 mm Hg, P < .001 and home BP (-6.4/-2.6 mm Hg, P < .01/P < .05) without side effects with 82% responders and good compliance. Conclusions: Resistant hypertensives can benefit from and are compliant with self-treatment by device-guided slow breathing.

Original languageEnglish
Pages (from-to)484-487
Number of pages4
JournalAmerican Journal of Hypertension
Issue number6
StatePublished - 1 Jun 2003
Externally publishedYes


  • Home blood pressure
  • Lifestyle modification
  • Nonpharmacologic therapy
  • Refractory hypertension
  • Respiratory pacing

ASJC Scopus subject areas

  • Internal Medicine


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