Nonspecific stimulation of cellular immunological responsiveness by a mycobacterial fraction

Oded Kuperman, Diane J. Yashphe, Shimon Sharf, Shlomo Ben-Efraim, David W. Weiss

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Pretreatment with a methanol insoluble moiety of BCG organisms, previously shown capable of heightening the resistance of experimental animals to tumor isografts and to spontaneous tumor development, markedly stimulated the subsequent immune response of mice to allogeneic cells and facilitated the development of delayed hypersensitivity of guinea pigs to an unrelated and otherwise non-immunogenic hapten-protein conjugate.

Original languageEnglish
Pages (from-to)277-282
Number of pages6
JournalCellular Immunology
Volume3
Issue number2
DOIs
StatePublished - 1 Jan 1972
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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