Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins

Karine Perié; Robert Marks; Sabine Szumerits; Serge Cosnier; Jean Paul Lellouche

doi:10.1016/S0040-4039(00)00475-5

Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins

Karine Perié, Robert Marks, Sabine Szumerits, Serge Cosnier, Jean Paul Lellouche

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	3725-3729
Number of pages	5
Journal	Tetrahedron Letters
Volume	41
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(00)00475-5
State	Published - 6 May 2000

Keywords

Biosensors
Bovine serum albumin
Chiral polymers
Polycarbazoles
Protein attachment

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/S0040-4039(00)00475-5

Cite this

@article{85c7f8d20726433292ec0103ca09da5e,

title = "Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins",

abstract = "Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.",

keywords = "Biosensors, Bovine serum albumin, Chiral polymers, Polycarbazoles, Protein attachment",

author = "Karine Peri{\'e} and Robert Marks and Sabine Szumerits and Serge Cosnier and Lellouche, {Jean Paul}",

note = "Funding Information: This work was generously supported by the Institute for Applied Biosciences (Ben-Gurion University of the Negev) through internal granting and a post-doctorate fellowship (K.P.) as well as by the Ministry of Science and the Arts. J.-P. Lellouche wishes to thank the Rashi Foundation for its financial support through the granting of a Guastella fellowship.",

year = "2000",

month = may,

day = "6",

doi = "10.1016/S0040-4039(00)00475-5",

language = "English",

volume = "41",

pages = "3725--3729",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "19",

}

TY - JOUR

T1 - Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins

AU - Perié, Karine

AU - Marks, Robert

AU - Szumerits, Sabine

AU - Cosnier, Serge

AU - Lellouche, Jean Paul

N1 - Funding Information: This work was generously supported by the Institute for Applied Biosciences (Ben-Gurion University of the Negev) through internal granting and a post-doctorate fellowship (K.P.) as well as by the Ministry of Science and the Arts. J.-P. Lellouche wishes to thank the Rashi Foundation for its financial support through the granting of a Guastella fellowship.

PY - 2000/5/6

Y1 - 2000/5/6

N2 - Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.

AB - Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.

KW - Biosensors

KW - Bovine serum albumin

KW - Chiral polymers

KW - Polycarbazoles

KW - Protein attachment

UR - http://www.scopus.com/inward/record.url?scp=0034612065&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)00475-5

DO - 10.1016/S0040-4039(00)00475-5

M3 - Article

AN - SCOPUS:0034612065

SN - 0040-4039

VL - 41

SP - 3725

EP - 3729

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 19

ER -

Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this