Novel electro-oxidizable chiral N-substituted dicarbazoles and resulting electroactive films for covalent attachment of proteins

Karine Perié, Robert Marks, Sabine Szumerits, Serge Cosnier, Jean Paul Lellouche

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations

    Abstract

    Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.

    Original languageEnglish
    Pages (from-to)3725-3729
    Number of pages5
    JournalTetrahedron Letters
    Volume41
    Issue number19
    DOIs
    StatePublished - 6 May 2000

    Keywords

    • Biosensors
    • Bovine serum albumin
    • Chiral polymers
    • Polycarbazoles
    • Protein attachment

    ASJC Scopus subject areas

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

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