Abstract
(Figure Presented) Promiscuous proteins: The identification and characterization of a wild-type promiscuous hydrolase that efficiently catalyzes the hydrolysis of ester bonds and haloacids in a single protein has been reported. This study has demonstrated the utility of metagenomics to access novel catalytic activities.
Original language | English |
---|---|
Pages (from-to) | 1975-1978 |
Number of pages | 4 |
Journal | ChemBioChem |
Volume | 11 |
Issue number | 14 |
DOIs | |
State | Published - 24 Sep 2010 |
Keywords
- Dehalogenases
- Esterases
- Hydrolysis
- Metagenomes
- Protein design
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Organic Chemistry