Novel NO biosensor based on the surface derivatization of GaAs by "hinged" iron porphyrins

Deng Guo Wu; Gonen Ashkenasy; Dmitry Shvarts; Rachel V. Ussyshkin; Ron Naaman; Abraham Shanzer; David Cahen

doi:10.1002/1521-3773(20001215)39:24<4496::AID-ANIE4496>3.0.CO;2-L

Novel NO biosensor based on the surface derivatization of GaAs by "hinged" iron porphyrins

Deng Guo Wu, Gonen Ashkenasy, Dmitry Shvarts, Rachel V. Ussyshkin, Ron Naaman, Abraham Shanzer, David Cahen

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

A tailor-made, two-component molecular system bound to a GaAs based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).

Original language	English
Pages (from-to)	4496-4500
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	39
Issue number	24
DOIs	https://doi.org/10.1002/1521-3773(20001215)39:24<4496::AID-ANIE4496>3.0.CO;2-L
State	Published - 15 Dec 2000
Externally published	Yes

Keywords

Biosensors
Nitrogen oxides
Porphyrinoids
Surface chemistry

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/1521-3773(20001215)39:24<4496::AID-ANIE4496>3.0.CO;2-L

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abstract = "A tailor-made, two-component molecular system bound to a GaAs based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).",

keywords = "Biosensors, Nitrogen oxides, Porphyrinoids, Surface chemistry",

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T1 - Novel NO biosensor based on the surface derivatization of GaAs by "hinged" iron porphyrins

AU - Wu, Deng Guo

AU - Ashkenasy, Gonen

AU - Shvarts, Dmitry

AU - Ussyshkin, Rachel V.

AU - Naaman, Ron

AU - Shanzer, Abraham

AU - Cahen, David

PY - 2000/12/15

Y1 - 2000/12/15

N2 - A tailor-made, two-component molecular system bound to a GaAs based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).

AB - A tailor-made, two-component molecular system bound to a GaAs based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).

KW - Biosensors

KW - Nitrogen oxides

KW - Porphyrinoids

KW - Surface chemistry

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U2 - 10.1002/1521-3773(20001215)39:24<4496::AID-ANIE4496>3.0.CO;2-L

DO - 10.1002/1521-3773(20001215)39:24<4496::AID-ANIE4496>3.0.CO;2-L

M3 - Article

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 24

ER -

Novel NO biosensor based on the surface derivatization of GaAs by "hinged" iron porphyrins

Abstract

Keywords

ASJC Scopus subject areas

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