Nuclear track-based biosensors with the enzyme laccase

H. García-Arellano, D. Fink, G. Muñoz Hernández, J. Vacík, V. Hnatowicz, L. Alfonta

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


A new type of biosensors for detecting phenolic compounds is presented here. These sensors consist of thin polymer foils with laccase-clad etched nuclear tracks. The presence of suitable phenolic compounds in the sensors leads to the formation of enzymatic reaction products in the tracks, which differ in their electrical conductivities from their precursor materials. These differences correlate with the concentrations of the phenolic compounds. Corresponding calibration curves have been established for a number of compounds. The sensors thus produced are capable to cover between 5 and 9 orders of magnitude in concentration - in the best case down to some picomoles. The sensor's detection sensitivity strongly depends on the specific compound. It is highest for caffeic acid and acid blue 74, followed by ABTS and ferulic acid.

Original languageEnglish
Pages (from-to)66-76
Number of pages11
JournalApplied Surface Science
StatePublished - 15 Aug 2014


  • Biosensor
  • Laccase
  • Nuclear tracks
  • Phenolic compounds

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics
  • General Physics and Astronomy
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films


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