Abstract
Latent inhibition (LI) is a phenomenon that reflects the ability to ignore irrelevant stimuli. LI is attenuated in some schizophrenic patient groups and in high schizotypal normal participants. One study has found enhanced LI in patients with obsessive-compulsive disorder (OCD [Swerdlow, N. R., Hartston, H. J., & Hartman, P. L., 1999. Enhanced visual latent inhibition in obsessive-compulsive disorder. Biological Psychiatry, 45, 482-488]). The present experiment replicated this finding using a within-subject visual search LI task, with OCD patients displaying more LI than healthy controls. The contrasting LI effects in schizophrenia and OCD are discussed in terms of how these groups differentially process relevant and irrelevant stimuli, and how that outcome affects subsequent behavior.
Original language | English |
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Pages (from-to) | 1137-1145 |
Number of pages | 9 |
Journal | Behaviour Research and Therapy |
Volume | 44 |
Issue number | 8 |
DOIs | |
State | Published - 1 Aug 2006 |
Externally published | Yes |
Keywords
- Anxiety
- Attention
- Latent inhibition
- Obsessive-compulsive disorder (OCD)
- Schizophrenia
- Visual search
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Clinical Psychology
- Psychiatry and Mental health