Obstetric and perinatal outcomes in women with eating disorders

Yael Pasternak, Adi Y. Weintraub, Ilana Shoham-Vardi, Ruslan Sergienko, Jonathan Guez, Arnon Wiznitzer, Hadar Shalev, Eyal Sheiner

    Research output: Contribution to journalArticlepeer-review

    25 Scopus citations

    Abstract

    Background: We wished to investigate whether women with a history of eating disorders have an increased risk for adverse obstetric and perinatal outcomes. Study design: A retrospective study was conducted comparing pregnancy complications in patients with and without eating disorders. Deliveries occurred during the years 1988-2009 in a tertiary medical center. Women lacking prenatal care and with multiple gestations were excluded from the study. Stratified analyses were performed using multivariable logistic regression models. Odds ratios (OR) and their 95% confidence interval (CI) were computed. A p value<0.05 was considered statistically significant. Results: During the study period, of 117,875 singleton deliveries, 122 (0.1%) occurred in patients with eating disorders. Eating disorders were significantly associated with fertility treatments (5.7% vs. 2.8%, p=0.047), intrauterine growth restriction (7.4% vs. 2.3%, p<0.001), term low birth weight (<2500g) (7.4% vs. 2.8%, p=0.002), preterm delivery (15.6% vs. 7.5%, p=0.002), and cesarean delivery (25.4% vs. 15.0%, p=0.001). Using multivariable analyses, low birth weight (OR 2.5, 95% CI 1.3-5.0), preterm delivery (OR 2.2, 95% CI 1.4-3.6), and cesarean section (OR 1.9, 95% CI 1.3-2.9) were significantly associated with eating disorders. Conclusions: Eating disorders are associated with increased risk of adverse pregnancy outcomes. Accordingly, careful surveillance is needed for early detection of possible complications.

    Original languageEnglish
    Pages (from-to)61-65
    Number of pages5
    JournalJournal of Women's Health
    Volume21
    Issue number1
    DOIs
    StatePublished - 1 Jan 2012

    ASJC Scopus subject areas

    • Medicine (all)

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