Obstructive apnea hypopnea index estimation by analysis of nocturnal snoring signals in adults

Nir Ben-Israel, Ariel Tarasiuk, Yaniv Zigel

Research output: Contribution to journalArticlepeer-review

80 Scopus citations


Study Objective: To develop a whole-night snore sounds analysis algorithm enabling estimation of obstructive apnea hypopnea index (AHIEST) among adult subjects. Design: Snore sounds were recorded using a directional condenser microphone placed 1 m above the bed. Acoustic features exploring intra-(melcepstability, pitch density) and inter-(running variance, apnea phase ratio, inter-event silence) snore properties were extracted and integrated to assess AHIEST. Setting: University-affiliated sleep-wake disorder center and biomedical signal processing laboratory. Patients: Ninety subjects (age 53 ± 13 years, BMI 31 ± 5 kg/m2) referred for polysomnography (PSG) diagnosis of OSA were prospectively and consecutively recruited. The system was trained and tested on 60 subjects. Validation was blindly performed on the additional 30 consecutive subjects. Measurements and Results: AHIEST correlated with AHI (AHIPSG; r2 = 0.81, P < 0.001). Area under the receiver operating characteristic curve of 85% and 92% for thresholds of 10 and 20 events/h, respectively, were obtained for OSA detection. Both Altman-Bland analysis and diagnostic agreement criteria revealed 80% and 83% agreements of AHIEST with AHIPSG, respectively. Conclusions: Acoustic analysis based on intra- and inter-snore properties can differentiate subjects according to AHI. An acoustic-based screening system may address the growing needs for reliable OSA screening tool. Further studies are needed to support these findings.

Original languageEnglish
Pages (from-to)1299-1305
Number of pages7
Issue number9
StatePublished - 1 Sep 2012


  • Acoustic analysis
  • Obstructive sleep apnea
  • Snoring

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)


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