On-chip detection of cellular activity

R. Almog, R. Daniel, S. Vernick, A. Ron, H. Ben-Yoav, Y. Shacham-Diamand

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

The use of on-chip cellular activity monitoring for biological/chemical sensing is promising for environmental, medical and pharmaceutical applications. The miniaturization revolution in microelectronics is harnessed to provide on-chip detection of cellular activity, opening new horizons for miniature, fast, low cost and portable screening and monitoring devices. In this chapter we survey different on-chip cellular activity detection technologies based on electrochemical, bio-impedance and optical detection. Both prokaryotic and eukaryotic cell-on-chip technologies are mentioned and reviewed.

Original languageEnglish
Title of host publicationAdvances in Biochemical Engineering/Biotechnology
EditorsT. Scheper
Pages179-191
Number of pages13
DOIs
StatePublished - 19 Aug 2010
Externally publishedYes

Publication series

NameAdvances in Biochemical Engineering/Biotechnology
Volume117
ISSN (Print)0724-6145

Keywords

  • Biochips
  • Bioluminescence
  • Biosensors
  • Electrochemical detection
  • Whole-cell

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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