[On efficient in vitro purification of cell suspensions containing malignant cells]

V. A. Namiot, E. A. Kogan, I. V. Filatov, M. S. Polishchuk, V. G. Tumanian, N. G. Esipova

Research output: Contribution to journalArticlepeer-review

Abstract

We propose a method for magnetic sorting of cell suspensions able to differentiate not only cells with single specific antigen on their surface, but also cells with a group of pre-defined antigens. Individually, each antigen of this group may be present on surfaces of non-selected cells. However, only the simultaneous presence of all given antigens on the cell surface means that such a cell should be separated. The method is of interest, for purification of cell suspensions from malignant cells, in particular, for purification of bone marrow material for autologous transplantation in leukemia.

Original languageEnglish
Pages (from-to)1121-1124
Number of pages4
JournalBiofizika
Volume59
Issue number6
StatePublished - 1 Jan 2014

ASJC Scopus subject areas

  • General Medicine

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