On efficient in vitro purification of cell suspensions containing malignant cells

V. A. Namiot; E. A. Kogan; I. V. Filatov; M. S. Polishchuk; V. G. Tumanyan; N. G. Esipova

doi:10.1134/S0006350914060128

On efficient in vitro purification of cell suspensions containing malignant cells

V. A. Namiot
, E. A. Kogan
, I. V. Filatov
, M. S. Polishchuk
, V. G. Tumanyan
, N. G. Esipova

Research output: Contribution to journal › Article › peer-review

Abstract

We have suggested a method for magnetic sorting of cell suspensions capable of differentiating not only the cells with a single specific antigen on their surface, but also those with a group of given antigens. Individually, each antigen of this group could be present on the surfaces of undesired cells. However, only the simultaneous presence of all the given antigens on the cell surface indicates that such a cell should be separated. The method is of interest for purification of cell suspensions from malignant cells—in particular, for purification of bone marrow material for autologous transplantation in leukemia.

Original language	English
Pages (from-to)	910-912
Number of pages	3
Journal	Biophysics (Russian Federation)
Volume	59
Issue number	6
DOIs	https://doi.org/10.1134/S0006350914060128
State	Published - 1 Jan 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

autologous transplantation in leukemia
magnetic cell sorting
simultaneous detection of antigen group

ASJC Scopus subject areas

Biophysics

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10.1134/S0006350914060128

Cite this

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title = "On efficient in vitro purification of cell suspensions containing malignant cells",

abstract = "We have suggested a method for magnetic sorting of cell suspensions capable of differentiating not only the cells with a single specific antigen on their surface, but also those with a group of given antigens. Individually, each antigen of this group could be present on the surfaces of undesired cells. However, only the simultaneous presence of all the given antigens on the cell surface indicates that such a cell should be separated. The method is of interest for purification of cell suspensions from malignant cells—in particular, for purification of bone marrow material for autologous transplantation in leukemia.",

keywords = "autologous transplantation in leukemia, magnetic cell sorting, simultaneous detection of antigen group",

author = "Namiot, \{V. A.\} and Kogan, \{E. A.\} and Filatov, \{I. V.\} and Polishchuk, \{M. S.\} and Tumanyan, \{V. G.\} and Esipova, \{N. G.\}",

note = "Publisher Copyright: {\textcopyright} 2014, Pleiades Publishing, Inc.",

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doi = "10.1134/S0006350914060128",

language = "English",

volume = "59",

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T1 - On efficient in vitro purification of cell suspensions containing malignant cells

AU - Namiot, V. A.

AU - Kogan, E. A.

AU - Filatov, I. V.

AU - Polishchuk, M. S.

AU - Tumanyan, V. G.

AU - Esipova, N. G.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - We have suggested a method for magnetic sorting of cell suspensions capable of differentiating not only the cells with a single specific antigen on their surface, but also those with a group of given antigens. Individually, each antigen of this group could be present on the surfaces of undesired cells. However, only the simultaneous presence of all the given antigens on the cell surface indicates that such a cell should be separated. The method is of interest for purification of cell suspensions from malignant cells—in particular, for purification of bone marrow material for autologous transplantation in leukemia.

AB - We have suggested a method for magnetic sorting of cell suspensions capable of differentiating not only the cells with a single specific antigen on their surface, but also those with a group of given antigens. Individually, each antigen of this group could be present on the surfaces of undesired cells. However, only the simultaneous presence of all the given antigens on the cell surface indicates that such a cell should be separated. The method is of interest for purification of cell suspensions from malignant cells—in particular, for purification of bone marrow material for autologous transplantation in leukemia.

KW - autologous transplantation in leukemia

KW - magnetic cell sorting

KW - simultaneous detection of antigen group

UR - https://www.scopus.com/pages/publications/84923825570

U2 - 10.1134/S0006350914060128

DO - 10.1134/S0006350914060128

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VL - 59

SP - 910

EP - 912

JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

IS - 6

ER -

On efficient in vitro purification of cell suspensions containing malignant cells

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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