On the effect of gadolinium in neutron capture therapy

Z. B. Alfassi; G. Shani; B. H. Laster

doi:10.1007/BF02349436

On the effect of gadolinium in neutron capture therapy

Z. B. Alfassi, G. Shani, B. H. Laster

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The possibility of (n,γ) reaction for cancer therapy is discussed in connection with gadolinium due to its exceptionally high cross section. It is argued that the therapeutic effect is not only due to Auger electrons but also to the recoil of the Gd atom. If the Gd atom is bound to the DNA it will cause several raptures in the same DNA molecule leading to death of the cancerous cells.

Original language	English
Pages (from-to)	687
Number of pages	1
Journal	Journal of Radioanalytical and Nuclear Chemistry
Volume	240
Issue number	2
DOIs	https://doi.org/10.1007/BF02349436
State	Published - 27 May 1999

ASJC Scopus subject areas

Analytical Chemistry
Nuclear Energy and Engineering
Radiology Nuclear Medicine and imaging
Pollution
Spectroscopy
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/BF02349436

Cite this

@article{46bf14e0aad74fbbaf2ceddd576a49be,

title = "On the effect of gadolinium in neutron capture therapy",

abstract = "The possibility of (n,γ) reaction for cancer therapy is discussed in connection with gadolinium due to its exceptionally high cross section. It is argued that the therapeutic effect is not only due to Auger electrons but also to the recoil of the Gd atom. If the Gd atom is bound to the DNA it will cause several raptures in the same DNA molecule leading to death of the cancerous cells.",

author = "Alfassi, {Z. B.} and G. Shani and Laster, {B. H.}",

year = "1999",

month = may,

day = "27",

doi = "10.1007/BF02349436",

language = "English",

volume = "240",

pages = "687",

journal = "Journal of Radioanalytical and Nuclear Chemistry",

issn = "0236-5731",

publisher = "Springer Netherlands",

number = "2",

}

TY - JOUR

T1 - On the effect of gadolinium in neutron capture therapy

AU - Alfassi, Z. B.

AU - Shani, G.

AU - Laster, B. H.

PY - 1999/5/27

Y1 - 1999/5/27

N2 - The possibility of (n,γ) reaction for cancer therapy is discussed in connection with gadolinium due to its exceptionally high cross section. It is argued that the therapeutic effect is not only due to Auger electrons but also to the recoil of the Gd atom. If the Gd atom is bound to the DNA it will cause several raptures in the same DNA molecule leading to death of the cancerous cells.

AB - The possibility of (n,γ) reaction for cancer therapy is discussed in connection with gadolinium due to its exceptionally high cross section. It is argued that the therapeutic effect is not only due to Auger electrons but also to the recoil of the Gd atom. If the Gd atom is bound to the DNA it will cause several raptures in the same DNA molecule leading to death of the cancerous cells.

UR - http://www.scopus.com/inward/record.url?scp=0032947956&partnerID=8YFLogxK

U2 - 10.1007/BF02349436

DO - 10.1007/BF02349436

M3 - Article

AN - SCOPUS:0032947956

SN - 0236-5731

VL - 240

SP - 687

JO - Journal of Radioanalytical and Nuclear Chemistry

JF - Journal of Radioanalytical and Nuclear Chemistry

IS - 2

ER -

On the effect of gadolinium in neutron capture therapy

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this