We summarize and elaborate on the recently published National Research Council report entitled "The Prevention and Treatment of Missing Data in Clinical Trials." We tailor our discussion to orthopaedic trials. In particular, we discuss the intent-to-treat principle, review study design and prevention ideas to minimize missing data, and present state-of-the-art sensitivity analysis methods for analyzing and reporting the results of studies with missing data.
|Number of pages||5|
|Journal||Journal of Bone and Joint Surgery|
|Issue number||SUPPL. 1|
|State||Published - 18 Jul 2012|
ASJC Scopus subject areas
- Orthopedics and Sports Medicine