Abstract
A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.
Original language | English |
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Article number | 154547 |
Journal | Tetrahedron Letters |
Volume | 123 |
DOIs | |
State | Published - 23 Jun 2023 |
Externally published | Yes |
Keywords
- Base promoted
- Dibenzofuran
- Domino synthesis
- Metal-free
- Multi-component reaction
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry