One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

Satyanaraya Reddy Jaggavarapu; Swadhapriya Bhukta; Rana Chatterjee; Venkateswara Rao Anna; Rambabu Dandela

doi:10.1016/j.tetlet.2023.154547

One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

Satyanaraya Reddy Jaggavarapu, Swadhapriya Bhukta, Rana Chatterjee, Venkateswara Rao Anna, Rambabu Dandela

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.

Original language	English
Article number	154547
Journal	Tetrahedron Letters
Volume	123
DOIs	https://doi.org/10.1016/j.tetlet.2023.154547
State	Published - 23 Jun 2023
Externally published	Yes

Keywords

Base promoted
Dibenzofuran
Domino synthesis
Metal-free
Multi-component reaction

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2023.154547

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title = "One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans",

abstract = "A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.",

keywords = "Base promoted, Dibenzofuran, Domino synthesis, Metal-free, Multi-component reaction",

author = "Jaggavarapu, \{Satyanaraya Reddy\} and Swadhapriya Bhukta and Rana Chatterjee and \{Rao Anna\}, Venkateswara and Rambabu Dandela",

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doi = "10.1016/j.tetlet.2023.154547",

language = "English",

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T1 - One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

AU - Jaggavarapu, Satyanaraya Reddy

AU - Bhukta, Swadhapriya

AU - Chatterjee, Rana

AU - Rao Anna, Venkateswara

AU - Dandela, Rambabu

PY - 2023/6/23

Y1 - 2023/6/23

N2 - A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.

AB - A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.

KW - Base promoted

KW - Dibenzofuran

KW - Domino synthesis

KW - Metal-free

KW - Multi-component reaction

UR - https://www.scopus.com/pages/publications/85159343260

U2 - 10.1016/j.tetlet.2023.154547

DO - 10.1016/j.tetlet.2023.154547

M3 - Article

AN - SCOPUS:85159343260

SN - 0040-4039

VL - 123

JO - Tetrahedron Letters

JF - Tetrahedron Letters

M1 - 154547

ER -

One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

Abstract

Keywords

ASJC Scopus subject areas

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