Onychomycosis: Rationalization of topical treatment

Avner Shemer, Henri Trau, Batya Davidovici, Boaz Amichai, Marcelo H. Grunwald

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Background: Fungal infection of the nail affect millions of people worlwide and has an estimated prevalence more than 10% of the general population. Objectives: To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis. Methods: We evaluated 331 patient with suspected clinical toenail onychomycosis affecting at least two toenails. Mycological examination of the affected nails was performed; both the KOH test and fungal culture were used. Results: Of 331 patients with suspected clinical toenail onychomycosis, 78.2% of the patients had at least three infected nails. The first toenail was the most affected. Trichophyton rubrum was by far the most common dermatophyte cultured from all samples. Conclusions: Most of the patients had at least three affected toenails. Topical treatment is not effective or practical, and systemic treatment should therefore be considered.

Original languageEnglish
Pages (from-to)415-416
Number of pages2
JournalIsrael Medical Association Journal
Issue number6
StatePublished - 13 Aug 2008
Externally publishedYes


  • Onychomycosis
  • Toenails
  • Treatment

ASJC Scopus subject areas

  • Medicine (all)


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