OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT

M. Lerner; D. Schwarzfuchs; Ilan Shelef; Yftach Gepner; N. Cohen; N. Bril; D. Serfaty; O. Tangi-Rosental; E. Goshen; S. Kanisboch; B. Sarusi; Rachel Golan; S. Witkow; Elad Shemesh; Yaakov Henkin; M.J. Stampfer; Assaf Rudich; Iris Shai

doi:10.1016/S0261-5614(13)60013-8

OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT

M. Lerner, D. Schwarzfuchs, Ilan Shelef, Yftach Gepner, N. Cohen, N. Bril, D. Serfaty, O. Tangi-Rosental, E. Goshen, S. Kanisboch, B. Sarusi, Rachel Golan, S. Witkow, Elad Shemesh, Yaakov Henkin, M.J. Stampfer, Assaf Rudich, Iris Shai

Research output: Contribution to journal › Meeting Abstract

Abstract

Rationale: It is unclear whether non-exercise activity thermogenesis (NEAT) from spontaneous activities is associated
with resting energy expenditure (REE) and abdominal fat subdepots.
Methods: We evaluated 270 participants with abdominal
obesity [waist circumference (WC)=107 cm, 32 women]using
gold-standard techniques to define NEAT, REE and abdominal
fat distribution. Each participant was assessed by accelerometer for six days to measure all performed movements. We
defined NEAT as 1 3 metabolic equivalents (METs) and nonspontaneous activity (NSA) as 4 9 METs. We used indirect
calorimetry to assess fasting REE and performed MRI imaging
to assess abdominal fat distribution at L5-L4.
Results: In multivariate regression models, adjusted for sex
and blood biomarkers, NEAT was independently associated
with increased REE/kg body weight (beta = 0.126; pv = 0.049)
and with decreased WC (beta = 0.137; pv = 0.037). Proportion
of NEAT from total activity time (TAT)/day was directly
associated with proportion of superficial subcutaneous fat
from total abdominal fat (beta = 0.141; pv = 0.003), and was
inversely associated with proportion of visceral fat from total
abdominal fat (beta = 0.142; pv = 0.011).
Conclusion: Increased energy expenditure from daily casual
activities might be beneficial for increased REE and for
improved abdominal fat distribution.

Original language	English
Pages (from-to)	S5
Journal	Clinical Nutrition
Volume	32
DOIs	https://doi.org/10.1016/S0261-5614(13)60013-8
State	Published - 1 Sep 2013

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10.1016/S0261-5614(13)60013-8

Cite this

Lerner, M., Schwarzfuchs, D., Shelef, I., Gepner, Y., Cohen, N., Bril, N., Serfaty, D., Tangi-Rosental, O., Goshen, E., Kanisboch, S., Sarusi, B., Golan, R., Witkow, S., Shemesh, E., Henkin, Y., Stampfer, M. J., Rudich, A., & Shai, I. (2013). OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT. Clinical Nutrition, 32, S5. https://doi.org/10.1016/S0261-5614(13)60013-8

@article{4a278e995c574bf6add56de516424875,

title = "OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT",

abstract = "Rationale: It is unclear whether non-exercise activity thermogenesis (NEAT) from spontaneous activities is associatedwith resting energy expenditure (REE) and abdominal fat subdepots.Methods: We evaluated 270 participants with abdominalobesity [waist circumference (WC)=107 cm, 32 women]usinggold-standard techniques to define NEAT, REE and abdominalfat distribution. Each participant was assessed by accelerometer for six days to measure all performed movements. Wedefined NEAT as 1 3 metabolic equivalents (METs) and nonspontaneous activity (NSA) as 4 9 METs. We used indirectcalorimetry to assess fasting REE and performed MRI imagingto assess abdominal fat distribution at L5-L4.Results: In multivariate regression models, adjusted for sexand blood biomarkers, NEAT was independently associatedwith increased REE/kg body weight (beta = 0.126; pv = 0.049)and with decreased WC (beta = 0.137; pv = 0.037). Proportionof NEAT from total activity time (TAT)/day was directlyassociated with proportion of superficial subcutaneous fatfrom total abdominal fat (beta = 0.141; pv = 0.003), and wasinversely associated with proportion of visceral fat from totalabdominal fat (beta = 0.142; pv = 0.011).Conclusion: Increased energy expenditure from daily casualactivities might be beneficial for increased REE and forimproved abdominal fat distribution.",

author = "M. Lerner and D. Schwarzfuchs and Ilan Shelef and Yftach Gepner and N. Cohen and N. Bril and D. Serfaty and O. Tangi-Rosental and E. Goshen and S. Kanisboch and B. Sarusi and Rachel Golan and S. Witkow and Elad Shemesh and Yaakov Henkin and M.J. Stampfer and Assaf Rudich and Iris Shai",

year = "2013",

month = sep,

day = "1",

doi = "10.1016/S0261-5614(13)60013-8",

language = "English",

volume = "32",

pages = "S5",

journal = "Clinical Nutrition",

issn = "0261-5614",

publisher = "Churchill Livingstone",

}

Lerner, M, Schwarzfuchs, D, Shelef, I, Gepner, Y, Cohen, N, Bril, N, Serfaty, D, Tangi-Rosental, O, Goshen, E, Kanisboch, S, Sarusi, B, Golan, R, Witkow, S, Shemesh, E, Henkin, Y, Stampfer, MJ, Rudich, A & Shai, I 2013, 'OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT', Clinical Nutrition, vol. 32, pp. S5. https://doi.org/10.1016/S0261-5614(13)60013-8

TY - JOUR

T1 - OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT

AU - Lerner, M.

AU - Schwarzfuchs, D.

AU - Shelef, Ilan

AU - Gepner, Yftach

AU - Cohen, N.

AU - Bril, N.

AU - Serfaty, D.

AU - Tangi-Rosental, O.

AU - Goshen, E.

AU - Kanisboch, S.

AU - Sarusi, B.

AU - Golan, Rachel

AU - Witkow, S.

AU - Shemesh, Elad

AU - Henkin, Yaakov

AU - Stampfer, M.J.

AU - Rudich, Assaf

AU - Shai, Iris

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Rationale: It is unclear whether non-exercise activity thermogenesis (NEAT) from spontaneous activities is associatedwith resting energy expenditure (REE) and abdominal fat subdepots.Methods: We evaluated 270 participants with abdominalobesity [waist circumference (WC)=107 cm, 32 women]usinggold-standard techniques to define NEAT, REE and abdominalfat distribution. Each participant was assessed by accelerometer for six days to measure all performed movements. Wedefined NEAT as 1 3 metabolic equivalents (METs) and nonspontaneous activity (NSA) as 4 9 METs. We used indirectcalorimetry to assess fasting REE and performed MRI imagingto assess abdominal fat distribution at L5-L4.Results: In multivariate regression models, adjusted for sexand blood biomarkers, NEAT was independently associatedwith increased REE/kg body weight (beta = 0.126; pv = 0.049)and with decreased WC (beta = 0.137; pv = 0.037). Proportionof NEAT from total activity time (TAT)/day was directlyassociated with proportion of superficial subcutaneous fatfrom total abdominal fat (beta = 0.141; pv = 0.003), and wasinversely associated with proportion of visceral fat from totalabdominal fat (beta = 0.142; pv = 0.011).Conclusion: Increased energy expenditure from daily casualactivities might be beneficial for increased REE and forimproved abdominal fat distribution.

AB - Rationale: It is unclear whether non-exercise activity thermogenesis (NEAT) from spontaneous activities is associatedwith resting energy expenditure (REE) and abdominal fat subdepots.Methods: We evaluated 270 participants with abdominalobesity [waist circumference (WC)=107 cm, 32 women]usinggold-standard techniques to define NEAT, REE and abdominalfat distribution. Each participant was assessed by accelerometer for six days to measure all performed movements. Wedefined NEAT as 1 3 metabolic equivalents (METs) and nonspontaneous activity (NSA) as 4 9 METs. We used indirectcalorimetry to assess fasting REE and performed MRI imagingto assess abdominal fat distribution at L5-L4.Results: In multivariate regression models, adjusted for sexand blood biomarkers, NEAT was independently associatedwith increased REE/kg body weight (beta = 0.126; pv = 0.049)and with decreased WC (beta = 0.137; pv = 0.037). Proportionof NEAT from total activity time (TAT)/day was directlyassociated with proportion of superficial subcutaneous fatfrom total abdominal fat (beta = 0.141; pv = 0.003), and wasinversely associated with proportion of visceral fat from totalabdominal fat (beta = 0.142; pv = 0.011).Conclusion: Increased energy expenditure from daily casualactivities might be beneficial for increased REE and forimproved abdominal fat distribution.

U2 - 10.1016/S0261-5614(13)60013-8

DO - 10.1016/S0261-5614(13)60013-8

M3 - Meeting Abstract

SN - 0261-5614

VL - 32

SP - S5

JO - Clinical Nutrition

JF - Clinical Nutrition

ER -

OPO11 NON-EXERCISE ACTIVITY THERMOGENESIS (NEAT) IS ASSOCIATED WITH INCREASED RESTING ENERGY EXPENDITURE, INCREASED SUPERFICIAL SUBCUTANEOUS FAT AND DECREASED VISCERAL FAT

Abstract

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