@inproceedings{f2dbb8317b2947c28b79b17a25b05a22,
title = "Optical properties of chlorin e6 in living melanoma cells",
abstract = "The tetrapyrrole chlorin e6 (Ce6) is actively used in photodynamic therapy (PDT) and as a test drug for sonodynamic therapy due to its ability to generate singlet oxygen. In this work, we have analyzed the absorption, photoluminescence (PL), and PL excitation spectra of Ce6 molecules in a nutrient medium and inside the melanoma cells. An analysis of the results shows that Ce6 inside the cancer cells with a low pH remains in monomeric form. A photodynamic test has also been conducted that confirmed the photodynamic effect produced by Ce6 in cancer cells by changing the signals from Ce6 and cells in the absorption and PL spectra.",
keywords = "Aggregation, Cancer, Chlorin e6, Monomers, Optical properties, Photodynamic therapy, Sensitizer, Singlet oxygen, Spectroscopy",
author = "Dadadzhanova, {Antonina I.} and Kolesova, {Ekaterina P.} and Maslov, {Vladimir G.} and Eliz Amar-Lewis and Riki Goldbart and Tamar Traitel and Joseph Kost and Orlova, {Anna O.}",
note = "Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation, GOSZADANIE No. 2019-1080. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Biomedical Spectroscopy, Microscopy, and Imaging 2020 ; Conference date: 06-04-2020 Through 10-04-2020",
year = "2020",
month = jan,
day = "1",
doi = "10.1117/12.2559066",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Jurgen Popp and Csilla Gergely",
booktitle = "Biomedical Spectroscopy, Microscopy, and Imaging",
address = "United States",
}
