Origin of the specificities of acetohydroxyacid synthases and glyoxylate carboligase

Keyphrases

• Glyoxylate Carboligase 100%
• Acetohydroxyacid Synthase 100%
• α-keto Acids 66%
• Product Release 50%
• α-ketobutyrate 50%
• Acceptor Substrate 50%
• Ethyl 16%
• Escherichia Coli 16%
• Fast Rates 16%
• Anions 16%
• Conformational Change 16%
• Decarboxylation 16%
• Condensation 16%
• Methyl 16%
• Major Determinants 16%
• Isozymes 16%
• Glyoxylate 16%
• Arginine 16%
• NMR Measurements 16%
• Carboxylate 16%
• Arginine Residue 16%
• Steric Hindrance 16%
• Aromatic Aldehydes 16%
• Mutant Enzyme 16%
• Rate-determining Step 16%
• Enamines 16%
• ThDP 16%
• Carboligation 16%
• Product Specificity 16%
• Alkyl Group 16%
• Acyl 16%
• Carbinols 16%
• 2-Hydroxy Acids 16%
• 2-hydroxybutyrate 16%
• Pharmaceutical Synthesis 16%

Biochemistry, Genetics and Molecular Biology

• Acetolactate Synthase 100%
• Arginine 33%
• Enzyme 16%
• Precursor 16%
• Conformational Change 16%
• Escherichia coli 16%
• Isozyme 16%
• Decarboxylation 16%
• Stereospecificity 16%