TY - JOUR
T1 - Outcomes of photorefractive keratectomy in patients with posterior corneal steepening
AU - Busool Abu-Eta, Yumna
AU - Nemet, Achia
AU - Vainer, Igor
AU - Mimouni, Michael
AU - Sela, Tzahi
AU - Munzer, Gur
AU - Kaiserman, Igor
N1 - Publisher Copyright:
© 2020, The Author(s), under exclusive licence to The Royal College of Ophthalmologists.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - Purpose: To assess post-operative outcomes following photorefractive keratectomy (PRK) in patients with posterior corneal steepening compared to an age, gender and refraction matched control group. Methods: A retrospective matched case-control study that analysed outcomes of PRK in eyes with posterior corneal steepening as shown by the Sirius tomography (Sirius, CSO, Italy), versus normal eyes. Both groups were age, gender and refraction matched. Data collected include: demographic data, pre-operative and post-operative refraction, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), maximal ablation depth. Inferior–superior ratio, central corneal thickness (CCT), mean posterior keratometry (K), Baiocchi Calossi Versaci index for the front (BCVf) and back (BCVb) cornea, the symmetry index of front (SIf) and back (SIb) corneal curvature were assessed pre- and postoperatively. Results: Overall, 89 study eyes and 954 normal myopic eyes were included. Compared to the control group, corneas with posterior steepening demonstrated significantly reduced CDVA (p < 0.0001 and p = 0.007) and lower CCT (p < 0.0001 and p = 0.03), before and following the operation, respectively. Pre-operative BCVf, BCVb, SIf and SIb were significantly higher in corneas with posterior steepening (p < 0.0001) and remained higher following the surgery except for BCVf. Ectasia occurred in one eye (1.1%). The safety and efficacy indices at 12 months were comparable for both groups. Conclusion: PRK on corneas with posterior steepening results in similar refractive outcomes compared to normal eyes, 1 year following the surgery. Keratectasia is a rare, however a possible complication.
AB - Purpose: To assess post-operative outcomes following photorefractive keratectomy (PRK) in patients with posterior corneal steepening compared to an age, gender and refraction matched control group. Methods: A retrospective matched case-control study that analysed outcomes of PRK in eyes with posterior corneal steepening as shown by the Sirius tomography (Sirius, CSO, Italy), versus normal eyes. Both groups were age, gender and refraction matched. Data collected include: demographic data, pre-operative and post-operative refraction, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), maximal ablation depth. Inferior–superior ratio, central corneal thickness (CCT), mean posterior keratometry (K), Baiocchi Calossi Versaci index for the front (BCVf) and back (BCVb) cornea, the symmetry index of front (SIf) and back (SIb) corneal curvature were assessed pre- and postoperatively. Results: Overall, 89 study eyes and 954 normal myopic eyes were included. Compared to the control group, corneas with posterior steepening demonstrated significantly reduced CDVA (p < 0.0001 and p = 0.007) and lower CCT (p < 0.0001 and p = 0.03), before and following the operation, respectively. Pre-operative BCVf, BCVb, SIf and SIb were significantly higher in corneas with posterior steepening (p < 0.0001) and remained higher following the surgery except for BCVf. Ectasia occurred in one eye (1.1%). The safety and efficacy indices at 12 months were comparable for both groups. Conclusion: PRK on corneas with posterior steepening results in similar refractive outcomes compared to normal eyes, 1 year following the surgery. Keratectasia is a rare, however a possible complication.
UR - http://www.scopus.com/inward/record.url?scp=85092103731&partnerID=8YFLogxK
U2 - 10.1038/s41433-020-01213-2
DO - 10.1038/s41433-020-01213-2
M3 - Article
C2 - 33024325
AN - SCOPUS:85092103731
SN - 0950-222X
VL - 35
SP - 2016
EP - 2023
JO - Eye (Basingstoke)
JF - Eye (Basingstoke)
IS - 7
ER -